Journal Publications
1
Management of iron deficiency in children, adults, and pregnant individuals: evidence-based and expert consensus recommendations
2025

Ashley E Benson, Jamie O Lo, Maureen O Achebe, Jorgeane S Aslan, Michael Auerbach, Bethany T Samuelson Bannow, Marie J Boller, Thomas G Deloughery, Jacquelin Dingman, Layla Van Doren, Geolani W Dy, Patricia A Ford, Jason A Freed, Michael K Georgieff, Kristina M Haley, Chloe I Han, Adam K Lewkowitz, Kylee L Martens, Robert T Means, Elizabeta Nemeth, Sven R Olson, Jacquelyn M Powers, Kristin C Prewitt, Toby Richards, Don C Rockey, Eric J Roeland, Kimberly S Ryan, Hanny Al-Samkari, Michelle Sholzberg, Methodius G Tuuli, Angela C Weyand, Michelle P Zeller, Annette M Totten, Ilya Ivlev, Joseph J Shatzel
2
Anticoagulation for Patients with Atrial Fibrillation Receiving Dialysis: A Pilot Randomized Controlled Trial
2025

Ziv Harel, Brendan Smyth, Sunil V Badve, Daniel Blum, William Beaubien-Souligny, Samuel A Silver, Edward Clark, Rita Suri, Thomas A Mavrakanas, Joanna Sasal, Bhanu Prasad, John Eikelboom, Karthik Tennankore, Claudio Rigatto, Ivana Prce, Francois Madore, Fabrice Mac-Way, Andrew Steele, Yangmin Zeng, Michelle Sholzberg, Paul Dorian, Andrew T Yan, Manish M Sood, David J Gladstone, Eric Tseng, Abhijat Kitchlu, Michael Walsh, Danny Sapir, Matthew J Oliver, Murali Krishnan, Mercedeh Kiaii, Nikki Wong, Sradha Kotwal, Marisa Battistella, Rey Acedillo, Charmaine Lok, Matthew Weir, Ron Wald
3
Genomic testing for bleeding disorders (GT4BD): protocol for a randomised controlled trial evaluating the introduction of whole genome sequencing early in the diagnostic pathway for patients with inherited bleeding disorders as compared with standard of care
2025

Megan Chaigneau, Mackenzie Bowman, Julie Grabell, Megan Conboy, Ana Johnson, Kevin Thorpe, Andrea Guerin, Rachelle Dinchong, Andrew Paterson, David Good, Alyson Mahar, Jeannie Callum, Laura Wheaton, Jennifer Leung, Roy Khalife, Michelle Sholzberg, David Lillicrap, Paula D James
5
Delphi consensus recommendations for neuraxial anesthesia in adults with platelet disorders and coagulation defects: communication from the ISTH SSC Subcommittee on von Willebrand Factor
2025

Wynn Peterson, Rachel Martin, Donald Arnold, Brendan Carvalho, Adam Cuker, Jeff Gadsden, Drew Provan, Natalia Rydz, Eliane Shore, David Kuter, Peter Kouides, Michelle Lavin, Paula James, Dale Engen, Michelle Sholzberg
6
Pregnancy loss in individuals with von Willebrand disease and unspecified mucocutaneous bleeding disorders: a multicenter cohort study
2025

Leslie Skeith, Paula James, Peter Kouides, Kelsey Uminski, Lisa Duffett, Shannon Jackson, Michelle Sholzberg, Margaret V Ragni, Adam Cuker, Maeve O’Beirne, Julia Hews-Girard, Natalia Rydz, Dawn M Goodyear, Jill Baxter, Andra James, David Garcia, Sara K Vesely, Man-Chiu Poon, VWD Pregnancy Loss Study Group
7
Efficacy and Safety Results With Rilzabrutinib, an Oral Bruton Tyrosine Kinase Inhibitor, in Patients With Immune Thrombocytopenia: Phase 2 Part B Study
2025
Nichola Cooper, AJ Gerard Jansen, Robert Bird, Jiří Mayer, Michelle Sholzberg, Michael D Tarantino, Mamta Garg, Paula F Ypma, Vickie McDonald, Charles Percy, Milan Košťál, Isaac Goncalves, Lachezar H Bogdanov, Terry B Gernsheimer, Remco Diab, Mengjie Yao, Ahmed Daak, David J Kuter
10
Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis
2024

WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Claire L Vale, Peter J Godolphin, David J Fisher, Julian PT Higgins, Alexandra McAleenan, Francesca Spiga, Tobias Tritschler, Pedro Gabriel Melo de Barros e Silva, David D Berg, Jeffrey S Berger, Lindsay R Berry, Behnood Bikdeli, Marc Blondon, Erin A Bohula, Marco Cattaneo, Riccardo Colombo, Valeria Coluccio, Maria T DeSancho, Michael E Farkouh, Valentin Fuster, Massimo Girardis, Judith S Hochman, Thomas P Jensen, Vivekanand Jha, Peter Jüni, Ajay J Kirtane, Patrick Lawler, Grégoire Le Gal, Ramon Lecumberri, Steven R Lentz, Renato D Lopes, Elizabeth Lorenzi, Marco Marietta, Carlos Henrique Miranda, Nuccia Morici, Susan C Morpeth, David A Morrow, Zoe K McQuilten, Nuria Muñoz-Rivas, Matthew D Neal, Suman Pant, Sahil A Parikh, Usha Perepu, Parham Sadeghipour, Sanjum Sethi, Michelle Sholzberg, Alex C Spyropoulos, Gregg W Stone, Azita Hajhossein Talasaz, Steven Tong, James Totterdell, Balasubramanian Venkatesh, Maddalena Alessandra Wu, Ryan Zarychanski, Stephane Zuily, Julie Viry, Jamie Rylance, Neill KJ Adhikari, Janet V Diaz, John C Marshall, Jonathan AC Sterne, Srinivas Murthy
14
Clinical and Economic Outcome Analysis of First-Line Immunosuppression in Acquired Hemophilia a
2024

Ellen Cusano, Julia Hews-Girard, Mujtaba Basharat, Lindsay Cowley, Julie Grabell, Nancy Hodgson, Kelly Pittman, Allison Rupnaraine, Rowan Thillaye-Kerr, Brendan Cord Lethebe, Paula James, Roy Khalife, Natasha Pardy, Chai W. Phua, Oksana C. Prokopchuk-Gauk, Michelle Sholzberg, Haowei Linda Sun, Man-Chiu Poon, M. Dawn Goodyear
16
Pregnancy loss in individuals with von Willebrand disease and unspecified mucocutaneous bleeding disorders: a multicenter cohort study
2024

Leslie Skeith, Paula James, Peter Kouides, Kelsey Uminski, Lisa Duffett, Shannon Jackson, Michelle Sholzberg, Margaret V Ragni, Adam Cuker, Maeve O’Beirne, Julia Hews-Girard, Natalia Rydz, Dawn M Goodyear, Jill Baxter, Andra James, David Garcia, Sara K Vesely, Man-Chiu Poon, VWD Pregnancy Loss Study Group
21
Use of antithrombotic therapy in patients with hemophilia: a selected synopsis of the European Hematology Association - International Society on Thrombosis and Haemostasis - European Association for Hemophilia and Allied Disorders - European Stroke Organization Clinical Practice Guidance document
2024

Miguel Escobar, Riitta Lassila, Carine Bekdache, Tarek Owaidah, Michelle Sholzberg
22
Pregnancy loss in individuals with von Willebrand disease and unspecified mucocutaneous bleeding disorders: a multicenter cohort study
2024

Leslie Skeith, Paula James, Peter Kouides, Kelsey Uminski, Lisa Duffett, Shannon Jackson, Michelle Sholzberg, Margaret V. Ragni, Adam Cuker, Maeve O’Beirne, Julia Hews-Girard, Natalia Rydz, Dawn M. Goodyear, Jill Baxter, Andra James, David Garcia, Sara K. Vesely, Man-Chiu Poon
29
Clinical and Economic Outcome Analysis of First-Line Immunosuppression in Acquired Hemophilia a
2024

Ellen Cusano, Julia Hews-Girard, Mujtaba Basharat, Lindsay Cowley, Julie Grabell, Nancy Hodgson, Kelly Pittman, Allison Rupnaraine, Rowan Thillaye-Kerr, Brendan Cord Lethebe, Paula James, Roy Khalife, Natasha Pardy, Chai W. Phua, Oksana C. Prokopchuk-Gauk, Michelle Sholzberg, Haowei Linda Sun, Man-Chiu Poon, M. Dawn Goodyear
35
2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19
2024

Sam Schulman, Donald M Arnold, Charlotte A Bradbury, Lisa Broxmeyer, Jean Marie Connors, Anna Falanga, Toshiaki Iba, Scott Kaatz, Jerrold H Levy, Saskia Middeldorp, Tracy Minichiello, Ishac Nazy, Eduardo Ramacciotti, Helaine E Resnick, Charles Marc Samama, Michelle Sholzberg, Jecko Thachil, Ryan Zarychanski, Alex C Spyropoulos, International Society on Thrombosis
36
Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress
2024

Chris Ward, Nicola Curry, Magdy El-Ekiaby, Kerstin Jurk, Henri H Versteeg, Charithani Keragala, Tal Burstyn-Cohen, Silvio Antoniak, Yuko Suzuki, Ross I Baker, Olivier Christophe, Shoshana Revel-Vilk, Alice Hart, Carsten Deppermann, Huyen Tran, Nicola Pozzi, Walter HA Kahr, Steven P Grover, Philip Wenzel, Ashley C Brown, Cécile Oury, Susan M Shea, James Fredenburgh, Freda H Passam, James Winearls, Hunter B Moore, Soumitra Tole, Eileen Merriman, Geoffrey D Barnes, Z Leonardo Liu, Michelle Sholzberg
38
Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP
2024

Lazaro Gil Gonzalez, Kevin D Won, Zoya Tawhidi, Emma Cummins, Yoelys Cruz-Leal, Yaima Tundidor Cabado, Ulrich J Sachs, Peter AA Norris, Yuexin Shan, Varsha Bhakta, Janessa Li, Ismael Samudio, Begonia Silva-Moreno, Liza Cerna-Portillo, Alequis Pavon Oro, Peter Bergqvist, Patrick Chan, Amy Moorehead, Michelle Sholzberg, William P Sheffield, Alan H Lazarus
40
Management of coagulopathy among patients with cirrhosis undergoing upper endoscopy and paracentesis: Persistent gaps and areas of consensus in a multispecialty Delphi
2024

Elliot B Tapper, Matthew A Warner, Rajesh P Shah, Juliet Emamaullee, Nancy M Dunbar, Michelle Sholzberg, Jacqueline N Poston, Robin J Soto, Ammar Sarwar, Anjana Pillai, Karina Reyner, Shivang Mehta, Marwan Ghabril, Timothy R Morgan, Stephen Caldwell
41
Anticoagulation for Patients with Atrial Fibrillation Receiving Dialysis: A Pilot Randomized Controlled Trial
2024

Ziv Harel, Brendan Smyth, Sunil V Badve, Daniel Blum, William Beaubien-Souligny, Samuel A Silver, Edward Clark, Rita Suri, Thomas A Mavrakanas, Joanna Sasal, Bhanu Prasad, John Eikelboom, Karthik Tennankore, Claudio Rigatto, Ivana Prce, Francois Madore, Fabrice Mac-Way, Andrew Steele, Yangmin Zeng, Michelle Sholzberg, Paul Dorian, Andrew T Yan, Manish M Sood, David J Gladstone, Eric Tseng, Abhijat Kitchlu, Michael Walsh, Danny Sapir, Matthew J Oliver, Murali Krishnan, Mercedeh Kiaii, Nikki Wong, Sradha Kotwal, Marissa Batisstella, Rey Acedillo, Charmaine Lok, Matthew Weir, Ron Wald
42
Use of antithrombotic therapy in patients with hemophilia: a selected synopsis of the European Hematology Association - International Society on Thrombosis and Haemostasis - European Association for Hemophilia and Allied Disorders - European Stroke Organization Clinical Practice Guidance document
2024

Miguel Escobar, Riitta Lassila, Carine Bekdache, Tarek Owaidah, Michelle Sholzberg
43
Randomized controlled trials of switching to a new medication vs continuing a chronic medication may underestimate the risk of adverse events in those continuing because of asymmetric depletion of susceptibles
2024

Michael Colacci, Afsaneh Raissi, Prachi Ray, Michelle Sholzberg, Kenneth J Rothman, Michael Fralick
44
Pregnancy loss in individuals with von Willebrand disease and unspecified mucocutaneous bleeding disorders: a multicenter cohort study
2024

Leslie Skeith, Paula James, Peter Kouides, Kelsey Uminski, Lisa Duffett, Shannon Jackson, Michelle Sholzberg, Margaret V. Ragni, Adam Cuker, Maeve O’Beirne, Julia Hews-Girard, Natalia Rydz, Dawn M. Goodyear, Jill Baxter, Andra James, David Garcia, Sara K. Vesely, Man-Chiu Poon
45
Thrombopoietin receptor agonists and other second-line therapies for Immune Thrombocytopenia: a narrative review with a focus on Drug Access in Canada
2024

Joanne Britto, Anne Holbrook, Haowei Sun, Christine Cserti-Gazdewich, Oksana Prokopchuk-Gauk, Cyrus Hsia, Karima Khamisa, Paul R Yenson, Michelle Sholzberg, Harold J Olney, Sudeep Shivakumar, David Jones, Hayley Merkeley, Jacqueline Costello, Erin Jamula, Donald M Arnold
47
Overview of the Safety Profile From Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases
2024

Michelle Sholzberg, Kelly Gwathmey, Catherine M Broome, Matthias Goebeler, Hiroyuki Murai, Zsuzsanna Bata-Csörgo, Adrian Newland, Peter Ulrichts, Rene Kerstens, Jeffrey T Guptill, Sofiane Agha, Ming Jiang, James F Howard Jr
54
Initial Report of Part B Phase 1/2 Efficacy and Safety Results for Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed Immune Thrombocytopenia
2023

Nichola Cooper, AJ Gerard Jansen, Robert Bird, Jiří Mayer, Michelle Sholzberg, Michael D Tarantino, Mamta Garg, Paula F Ypma, Vickie McDonald, Charles Percy, Milan Košťál, Isaac Goncalves, Lachezar H Bogdanov, Terry B Gernsheimer, Remco Diab, Mengjie Yao, Ahmed Daak, David J Kuter
58
Defining Ferritin Clinical Decision Limits to Improve Diagnosis and Treatment of Iron Deficiency: A Modified Delphi Study
2022

Kanza Naveed, Nicola Goldberg, Eliane Shore, Arti Dhoot, Denise Gabrielson, Zahra Goodarzi, Yulia Lin, Menaka Pai, Natasha A Pardy, Sue Robinson, Roseann Andreou, Manish Sood, Victoria Price, Ashley Verduyn, Michelle L Parker, Michael Fralick, Daniel Beriault, Michelle Sholzberg
60
Take Control. Period.-Interactive Patient Education Website Enhances Adherence to Tranexamic Acid and Iron Supplementation in Women with Heavy Menstrual Bleeding
2022

Savannah Norman, Ying Ling, Meffe Filomena, Shamshah Aratia, Deborah Robertson, Aziz Jiwajee, Grace Tang, Paula D James, Jeff Mosko, Michelle Sholzberg
66
COVID-19-associated pulmonary embolism: review of the pathophysiology, epidemiology, prevention, diagnosis, and treatment
2022

Luis Ortega-Paz, Azita H Talasaz, Parham Sadeghipour, Tatjana S Potpara, Herbert D Aronow, Luis Jara-Palomares, Michelle Sholzberg, Dominick J Angiolillo, Gregory YH Lip, Behnood Bikdeli
67
ISTH guidelines for antithrombotic treatment in COVID‐19
2022

Sam Schulman, Michelle Sholzberg, Alex C Spyropoulos, Ryan Zarychanski, Helaine E Resnick, Charlotte A Bradbury, Jean Marie Connors, Anna Falanga, Toshiaki Iba, Scott Kaatz, Jerrold H Levy, Saskia Middeldorp, Tracy Minichiello, Eduardo Ramacciotti, Charles Marc Samama, Jecko Thachil, Lisa Broxmeyer, International Society on Thrombosis
68
Evaluating the Impact of Daily Versus Every Other Day Oral Iron Supplementation in Patients with Iron Deficiency Anemia: A Pilot Feasibility Trial
2022

Yulia Lin, M Elisabeth Del Giudice, Amie T Kron, Harley Meirovich, Michelle Sholzberg, Christine Cserti-Gazdewich, Vidushi Swarup, Mary Huang, Lanis DiStefano, Waseem Anani, Chantal Armali, Jeannie Callum
72
The association between diabetes and mortality among patients hospitalized with COVID-19: Cohort Study of Hospitalized Adults in Ontario, Canada and Copenhagen, Denmark
2022

Orly Bogler, Afsaneh Raissi, Michael Colacci, Andrea Beaman, Tor Biering-Sørensen, Alex Cressman, Allan Detsky, Alexi Gosset, Mats Højbjerg Lassen, Chris Kandel, Yaariv Khaykin, David Barbosa, Lauren Lapointe Shaw, Derek R MacFadden, Alexander Pearson, Bruce Perkins, Kenneth J Rothman, Kristoffer Grundtvig Skaarup, Rachael Weagle, Chris Yarnell, Michelle Sholzberg, Bena Hodzic-Santor, Erik Lovblom, Jonathan Zipursky, Kieran L Quinn, Mike Fralick
77
Daily versus every other day oral iron supplementation in patients with iron deficiency anemia (DEODO): study protocol for a phase 3 multicentered, pragmatic, open-label, pilot randomized controlled trial
2022

Amie Kron, M Elisabeth Del Giudice, Michelle Sholzberg, Jeannie Callum, Christine Cserti-Gazdewich, Vidushi Swarup, Mary Huang, Lanis Distefano, Waseem Anani, Robert Skeate, Chantal Armali, Yulia Lin
84
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia
2022

Manraj N Kaur, Donald M Arnold, Nancy M Heddle, Richard J Cook, Cyrus Hsia, Mark Blostein, Erin Jamula, Michelle Sholzberg, Yulia Lin, Jeannine Kassis, Loree Larratt, Alan Tinmouth, Julie Carruthers, Na Li, Yang Liu, Feng Xie
88
Randomized trials of therapeutic heparin for COVID‐19: a meta‐analysis
2021

Michelle Sholzberg, Bruno R da Costa, Grace H Tang, Hassan Rahhal, Musaad AlHamzah, Lisa Baumann Kreuziger, Fionnuala Ní Áinle, Mozah Obaid Almarshoodi, Paula D James, David Lillicrap, Marc Carrier, Andrew Beckett, Michael Fralick, Saskia Middeldorp, Agnes YY Lee, Kevin E Thorpe, Elnara Marcia Negri, Mary Cushman, Peter Jüni, RAPID Trial Investigators
90
Coagulopathy of hospitalised COVID-19: A Pragmatic Randomised Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG – RAPID Trial): A structured summary of a study protocol for a randomised controlled trial
2021

Michelle Sholzberg, Grace H Tang, Elnara Negri, Hassan Rahhal, Lisa Baumann Kreuziger, Carlos E Pompilio, Paula James, Michael Fralick, Musaad AlHamzah, Faris Alomran, Eric Tseng, Gloria Lim, David Lillicrap, Marc Carrier, Fionnuala Ní Áinle, Andrew Beckett, Bruno R da Costa, Kevin Thorpe, Saskia Middeldorp, Agnes Lee, Mary Cushman, Peter Jüni
93
Effect of antithrombotic therapy on clinical outcomes in outpatients with clinically stable symptomatic COVID-19: the ACTIV-4B randomized clinical trial
2021

Jean M Connors, Maria M Brooks, Frank C Sciurba, Jerry A Krishnan, Joseph R Bledsoe, Andrei Kindzelski, Amanda L Baucom, Bridget-Anne Kirwan, Heather Eng, Deborah Martin, Elaine Zaharris, Brendan Everett, Lauren Castro, Nancy L Shapiro, Janet Y Lin, Peter C Hou, Carl J Pepine, Eileen Handberg, Daniel O Haight, Jason W Wilson, Sarah Majercik, Zhuxuan Fu, Yongqi Zhong, Vidya Venugopal, Scott Beach, Steve Wisniewski, Paul M Ridker, Scott Brakenridge, Eric Leifer, Andrea Troxel, Aldo Maggioni, Jeff Jacobson, Renato D Lopes, Rob Mentz, Michelle Sholzberg, John H Alexander, Donald Schreiber, Kabir Yadav, Anthony Vecchiarelli, Godson Oguchi, Lisa Merck, Victoria Altagracia, Antonio Gonzalez, Dominick Angiolillo, Fred Blind, John Cienki, Reinaldo Loy, Eddie Armas, Juvenal Martinez, Juan Ruiz Unger, Vishal Gulati, Temple Robinson, Claudia Kroker-Bode, Jason Wilson, David Beiser, Maggie Hagan, Jonathan Cohen, Sascha Goonewardena, Jeffrey Fletcher, Rowena Dolor, Thomas Jarrett, Vijay Patel, Ming-Li Wang, Nicole Acquisto, Anderson Mehrle, Khetpal Saangeeta, Nicholas Hanna, Hassan Abouhouli, Alexandra Weissman, Raman Purighalla, Nathan Bennett, Gregory Jay, David Barbham, TJ Milling, Dalla Abdelsayed, David McPherson, Patricia Salvato, Chukwumeka Orgwu, Anuradha Mundluru, Patti Olusola, William Lewis, ACTIV-4B Investigators
94
Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial
2021

Michelle Sholzberg, Grace H Tang, Hassan Rahhal, Musaad AlHamzah, Lisa Baumann Kreuziger, Fionnuala Ní Áinle, Faris Alomran, Khalid Alayed, Mohammed Alsheef, Fahad AlSumait, Carlos Eduardo Pompilio, Catherine Sperlich, Sabrena Tangri, Terence Tang, Peter Jaksa, Deepa Suryanarayan, Mozah Almarshoodi, Lana A Castellucci, Paula D James, David Lillicrap, Marc Carrier, Andrew Beckett, Christos Colovos, Jai Jayakar, Marie-Pier Arsenault, Cynthia Wu, Karine Doyon, E Roseann Andreou, Vera Dounaevskaia, Eric K Tseng, Gloria Lim, Michael Fralick, Saskia Middeldorp, Agnes YY Lee, Fei Zuo, Bruno R Da Costa, Kevin E Thorpe, Elnara Márcia Negri, Mary Cushman, Peter Jüni
95
The impact of extended half‐life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B
2021

Haowei Linda Sun, Ming Yang, Man‐Chiu Poon, Adrienne Lee, K Sue Robinson, Michelle Sholzberg, John Wu, Alfonso Iorio, Victor Blanchette, Manuel Carcao, Robert J Klaassen, Shannon Jackson
96
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half‐life concentrates: a Canadian observational study of real‐world outcomes
2021

Haowei Sun, Ming Yang, Man‐Chiu Poon, Adrienne Lee, K Sue Robinson, Michelle Sholzberg, John Wu, Alfonso Iorio, Victor Blanchette, Manuel Carcao, Robert J Klaassen, Shannon Jackson
High prevalence of iron deficiency and socioeconomic disparities in laboratory screening of non‐pregnant females of reproductive age: A retrospective cohort study




2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19


Management of coagulopathy among patients with cirrhosis undergoing upper endoscopy and paracentesis: Persistent gaps and areas of consensus in a multispecialty Delphi
Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP
Randomized controlled trials of switching to a new medication vs continuing a chronic medication may underestimate the risk of adverse events in those continuing because of asymmetric depletion of susceptibles
Tranexamic acid for management of heavy vaginal bleeding: barriers to access and myths surrounding its use
Thrombopoietin receptor agonists and other second-line therapies for Immune Thrombocytopenia: a narrative review with a focus on Drug Access in Canada






Overview of the Safety Profile From Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases

Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia


What have we learned about the patient's experience of von Willebrand disease? A focus on women

The Empower Study - Design of a Randomized Clinical Trial to Assess the Efficacy and Safety of a Plasma-Derived Von Willebrand Factor / Factor VIII Concentrate for Heavy Menstrual Bleeding in Women with Von Willebrand Disease
Pregnancy in Patients with Immune Thrombotic Thrombocytopenic Purpura (iTTP): Single Centre Experience and Review of Literature


Defining Ferritin Clinical Decision Limits to Improve Diagnosis and Treatment of Iron Deficiency: A Modified Delphi Study


Take Control. Period.-Interactive Patient Education Website Enhances Adherence to Tranexamic Acid and Iron Supplementation in Women with Heavy Menstrual Bleeding
Isolated thrombocytopenia in older adults is associated with the diagnosis of hematologic malignancy: a population-based study


International normalized ratio and activated partial thromboplastin time screening tests
Tests de dépistage du rapport international normalisé et du temps de céphaline activée


Reducing use of coagulation tests in a family medicine practice setting: An implementation study



COVID-19-associated pulmonary embolism: review of the pathophysiology, epidemiology, prevention, diagnosis, and treatment


Evaluating the Impact of Daily Versus Every Other Day Oral Iron Supplementation in Patients with Iron Deficiency Anemia: A Pilot Feasibility Trial

Lymphoma‐associated acquired von Willebrand syndrome responsive to splenectomy: A case report
Iron surveillance and management in gastrointestinal oncology patients: A national survey of physician practice.



The association between diabetes and mortality among patients hospitalized with COVID-19: Cohort Study of Hospitalized Adults in Ontario, Canada and Copenhagen, Denmark

Iron surveillance and management in gastrointestinal oncology patients: A national survey of physician practice


Pharmacologic thromboprophylaxis for patients admitted to general medicine—is it necessary?
Daily versus every other day oral iron supplementation in patients with iron deficiency anemia (DEODO): study protocol for a phase 3 multicentered, pragmatic, open-label, pilot randomized controlled trial


Health issues in women and girls affected by haemophilia with a focus on nomenclature, heavy menstrual bleeding, and musculoskeletal issues


Evaluation of definitions for oral anticoagulant-associated major bleeding: A population-based cohort study
Coagulation test understanding and ordering by medical trainees: Novel teaching approach


Evaluating Rates of Preoperative Medical Optimization to Correct Anemia in Patients Undergoing Myomectomy


Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia


Sex specific definitions of anaemia contribute to health inequity and sociomedical injustice

Cross-reacting antiporcine factor VIII inhibitors in patients with acquired hemophilia A


Increased risk of haematological malignancy in adults over age 60 with thrombocytopenia compared with matched controls: Time for an upfront bone marrow evaluation?

Sex Differences in Anemia and Red Blood Cell Transfusions Among General Internal Medicine Inpatients
Coagulopathy of hospitalised COVID-19: A Pragmatic Randomised Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG – RAPID Trial): A structured summary of a study protocol for a randomised controlled trial
Suboptimal iron deficiency screening in pregnancy and the impact of socioeconomic status in a high-resource setting
Effect of antithrombotic therapy on clinical outcomes in outpatients with clinically stable symptomatic COVID-19: the ACTIV-4B randomized clinical trial
Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial
The impact of extended half‐life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half‐life concentrates: a Canadian observational study of real‐world outcomes
Recognize, treat and report cases of vaccine-induced thrombotic immune thrombocytopenia
Reconnaître, traiter et signaler les cas de thrombocytopénie immunitaire thrombotique induite par un vaccin
Safety of idarucizumab in the reversal of dabigatran at six tertiary care Ontario hospitals
Recognizing, managing and reporting vaccine-induced immune thrombotic thrombocytopenia
Real-World Data on the Effectiveness and Safety of wilate for the Treatment of von Willebrand Disease
“They don’t really take my bleeds seriously”: Barriers to care for women with inherited bleeding disorders
Vaccine induced immune thrombotic thrombocytopenia (VITT) following adenovirus vector COVID-19 vaccination: interim guidance for healthcare professionals in the outpatient setting
Evaluating hemostatic thresholds for neuraxial anesthesia in adults with hemorrhagic disorders and tendencies: A scoping review
Observational study of efficacy and safety of human cell line–derived recombinant factor VIII in Canadian adults with moderately severe and severe haemophilia A.
The problem with population data for the determination of ferritin lower reference interval limits.
Impact of a blood conservation bundle checklist on perioperative transfusion rates during myomectomy
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review
Extended half‐life factor VIII concentrates in adults with hemophilia A: Comparative pharmacokinetics of two products
Antithrombotic therapy in COVID-19: systematic summary of ongoing or completed randomized trials

“Everything was blood when it comes to me”: Understanding the lived experiences of women with inherited bleeding disorders
Hemorrhagic, thrombotic and obstetric complications of congenital dysfibrinogenemia in a previously asymptomatic woman


The contribution of iron deficiency to the risk of peripartum transfusion: a retrospective case control study
New mutation found to cause hereditary thrombotic thrombocytopenic purpura in a patient presenting with seizures in adulthood


Administration of Neuraxial Anesthesia in Adults with Pre-Existing Bleeding Disorders and Tendencies: Methodology for Delphi Consensus Recommendations
Experience with Continuous Infusion of Recombinant Porcine FVIII in Patients with Acquired Hemophilia a
Establishing Clinical Decision Limits for Serum B12 Deficiency: Using Modified Delphi Methodology



A Retrospective Cohort Study Evaluating the Safety and Efficacy of Peri-Partum Tranexamic Acid for Women with Inherited Bleeding Disorders


A Major Knowledge Gap in Women's Health: The Combined Effect of Antifibrinolytics and Estrogen on Risk of Thromboembolism-a Scoping Review
Anticoagulant interventions in hospitalized patients with COVID‐19: A scoping review of randomized controlled trials and call for international collaboration


Describing the point prevalence and characteristics of venous thromboembolism in patients with thrombotic thrombocytopenic purpura

Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial


Fostamatinib is an effective second‐line therapy in patients with immune thrombocytopenia
The development of a quality improvement project to improve infection prevention and management in patients with asplenia or hyposplenia


The evolution of hemophilia care: clinical and laboratory advances, opportunities, and challenges




Increasing awareness and capacity outside of a tertiary care hemophilia treatment centre
The Factor Concentrate Redistribution Program: going beyond short dating product redistribution


Proof-of-principle in a large animal pilot: cardiac arrest may be associated with acute, transient coagulopathy that may drive post-cardiac arrest syndrome


Impact of an intraoperative “Blood Conservation Bundle” on perioperative transfusion rates during myomectomy
The development of a standardized provincial massive hemorrhage protocol with a built-in continuous quality improvement framework


A Non-Inferiority Trial of Perioperative Eltrombopag or Intravenous Immune Globulin for Immune Thrombocytopenia
Healthcare provider perspectives on inequities in access to care for patients with inherited bleeding disorders


International Network of VENous Thromboembolism Clinical Research Networks INVENT-VTE. Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration
Confounding effect of therapeutic protamine and heparin levels on routine and special coagulation testing


Delphi approach for the design of an intraoperative blood conservation pathway for open myomectomy
The safety and efficacy of ferumoxytol in the treatment of iron deficiency: a systematic review and meta‐analysis
Bone health in symptomatic carriers of haemophilia A: a protocol for a multicentre prospective matched-cohort study
Enhanced responses to Fostamatinib as second-line therapy and in persistent Immune Thrombocytopenia (ITP) patients
The Frequency and Effect of Baseline Cross-Reacting and De Novo Inhibitors to Recombinant Porcine FVIII in Patients with Congenital and Acquired Hemophilia a
A Regional Massive Hemorrhage Protocol: Designed with a Modified Delphi Technique to Obtain Consensus
Perioperative Eltrombopag or Intravenous Immune Globulin for Patients with Immune Thrombocytopenia: A Multicenter Randomized Trial
Reducing repetitive and reflexive diagnostic phlebotomy in an intensive care unit: a quality improvement project
Take Control. Period. - Needs Assessment Leading to the Development of a Digital Quality Improvement Intervention Designed to Enhance Adherence to Tranexamic Acid and Iron Supplementation in Women with Heavy Menstrual Bleeding
“Everything Was Blood When It Comes to Me”: Understanding the Lived Experiences of Women with Inherited Bleeding Disorders
Barriers to Care Amongst Patients with Inherited Bleeding Disorders: Results from Two Nation-Wide Canadian Surveys
Can an Online Educational Module Improve Medical Trainee Confidence and Knowledge of Coagulation?
Prevalence of iron deficiency and iron deficiency anemia during pregnancy: a single centre Canadian study
Describing the Point Prevalence and Characteristics of Venous Thromboembolism in Patients with Thrombotic Thrombocytopenic Purpura
Impact of a “Blood Conservation Bundle” on Perioperative Transfusion Rates During Myomectomy
D-DIMER TESTING: A 6 YEAR REVIEW OF PROFICIENCY TESTING DATA FROM THE INSTITUTE FOR QUALITY MANAGEMENT IN HEALTHCARE (IQMH).
EVALUATION OF ONE-STAGE APTT-BASED FACTOR IX ASSAYS FOR MONITORING N9-GP (REBINYN), A RECOMBINANT PEGYLATED FIX CONCENTRATE.
Appropriateness of intravenous immunoglobulin use in immune thrombocytopenia (ITP): A Canadian centre deep dive audit
Development and implementation of a quality improvement toolkit, iron deficiency in pregnancy with maternal iron optimization (IRON MOM): a before-and-after study
Family ties: Two cases of congenital dysfibrinogenemia during pregnancy
Intravenous iron versus oral iron or observation for gastrointestinal malignancies: a systematic review
Gaucher disease screening at a general adult hematology tertiary care centre: A prospective study
Acquired haemophilia A and concomitant factor XIII consumption.
Response: patient blood management strategies for iron-deficiency anemia management in gastric cancer
Exploring the effect of factor Xa inhibitors on rotational thromboelastometry: a case series of bleeding patients
Peri-operative eltrombopag or immune globulin for patients with immune thrombocytopaenia (The Bridging ITP Trial): methods and rationale
Safety and efficacy of pdVWF/FVIII in patients with von Willebrand disease undergoing surgery: Results from a non-interventional multicentre study



Two-year safety and efficacy outcomes with fostamatinib in adult patients with immune thrombocytopenia (ITP): open-label extension to phase 3 trial program



Reducing Unnecessary Coagulation Testing in Outpatients (REDUCTION): A Quality Improvement Project



The Safety and Efficacy of Ferumoxytol in the Treatment of Iron Deficiency: A Systematic Review and Meta-Analysis
Are There Inequities in Access to Care Amongst Women with Inherited Bleeding Disorders? a Systematic Review


Observational study of real-world factor utilization and health outcomes in patients with hemophilia in Canada



A Retrospective Assessment of Prevention and Treatment of Iron Deficiency Amongst Patients Requiring Peripartum Transfusion

Coagulation test interpretation in a patient taking direct oral anticoagulant therapy
EFFECT OF DIRECT ORAL ANTICOAGULANTS ON FIBRINOGEN INDUCED PSEUDOPARAPROTEINEMIA


Retrospective review of Acquired Haemophilia A from the largest Canadian Haemophilia treatment centre.
Reducing unnecessary coagulation testing in outpatients: A quality improvement project


PERSPECTIVES ON PROPHYLACTIC FACTOR REPLACEMENT FROM ADULT PATIENTS WITH MODERATE AND SEVERE HEMOPHILIA
Tackling overutilization of hospital tests and treatments: Lessons learned from a grassroots approach


RESEARCH DATABASE FOR THE MULTIDISCIPLINARY CLINIC FOR WOMEN WITH BLEEDING DISORDERS
Novel assays in the coagulation laboratory: a clinical and laboratory perspective


Haemophilia commentary: The utility of BAT s
A Delphi Approach for the Design of an Intra-Operative Blood Conservation Pathway at Open Myomectomy


Enhancing postpartum care of women with bleeding disorders through awareness and self-empowerment
A sticky situation: myocardial infarction in a young woman with immune thrombocytopenia on eltrombopag and a history of mediastinal radiation


Hemostatic Abnormalities in the Critically Ill
Gaucher Disease Screening at a General Adult Haematology Referral, Single Tertiary Care Centre: A Prospective Study


Laparoscopic splenectomy for resistant immune thrombocytopenia in pregnancy: a case report and review of literature
Quality Improvement in the Care of Patients with Asplenia: Focus on Diminishing Risk of Infection
Reduced 2: Reducing Unnecessary Coagulation Testing in the Emergency Department, Stage 2
The Anticoagulated trauma patient in the age of the direct oral anticoagulants: a Canadian perspective
OVERUTILIZATION OF LAB TESTS IN MEDICINE: ACHIEVING SMART TESTING THROUGH COLLABORATION.
Iron deficiency anemia in gastric cancer: A Canadian single site retrospective cohort study
Coagulation Testing in a Bleeding Patient
Effect of moderate intensity exercise on haemostatic capacity in adults with haemophilia A and B: pilot study.
Recombinant porcine sequence factor VIII (rp FVIII) for acquired haemophilia A: practical clinical experience of its use in seven patients
REDucing unnecessary coagulation testing in the emergency department (REDUCED)

Interim Canadian Data from a Prospective, Observational Study of Routine Clinical Use of a Von Willebrand Factor Concentrate (Wilate®)


Surgery in Patients with Factor VIII Inhibitors: A Retrospective Case Series at the Largest Canadian Hemophilia Care Centre
Diagnosis and Outcomes of Patients Presenting with Microangiopathic Hemolytic Anemia and Thrombocytopenia to a University Hospital Apheresis Unit




TEMPORAL TRENDS IN ACQUIRED HEMOPHILIA A: A RETROSPECTIVE 32 YEAR CASE SERIES FROM THE LARGEST CANADIAN ADULT HEMOPHILIA TREATMENT CENTER
PRACTICAL CLINICAL EXPERIENCE WITH RECOMBINANT PORCINE FVIII FOR ACQUIRED HEMOPHILIA A


Increasing patient understanding of factor VIII concentrate pharmacokinetics and improving patient engagement using myPKFiT
A Comprehensive Online Communication and Education Strategy for Hemophilia Treatment Centers


Effect of moderate intensity exercise on hemostatic capacity in adults with hemophilia A and B: Pilot study
Integrated multidisciplinary care for the management of chronic conditions in adults: an overview of reviews and an example of using indirect evidence to inform clinical practice recommendations in the field of rare diseases



Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study
The anticoagulated trauma patient: a Canadian experience in the era of direct oral anticoagulants


A quality improvement initiative to optimize appropriate testing for venous thromboembolism in the emergency department

Successful immune tolerance induction with von Willebrand factor containing concentrate in an adult with haemophilia A and chronic inhibitor-a case study.
The influence of socioeconomic status on selection of anticoagulation for atrial fibrillation


Direct oral anticoagulants and the bleeding patient
The influence of socioeconomic status on selection of anticoagulation for atrial fibrillation: A population based study

Persistent thrombopoietin mimetic induced myelofibrosis in a woman with chronic refractory immune thrombocytopenia
Arteriovenous fistulas for replacement therapy in adults with hemophilia
Successful immune tolerance induction in an adult with hemophilia a and chronic inhibitor-a case study
Heparin and protamine confound factor activity and inhibitor testing while on cardiopulmonary bypass
Assessment of Recombinant Factor IX Fc Fusion Protein (rFIXFc) Clotting Activity in Plasma Samples at Canadian Hemophilia Treatment Centres

Genotype Phenotype Correlation in Patients with aHUS and Abnormal Genetic Studies: A Single Centre Experience
Safety and efficacy of thrombopoietin‐receptor agonists in myelodysplastic syndromes: a systematic review and meta‐analysis of randomized controlled trials


CASE SERIES: BLEEDING COMPLICATIONS FROM THE NOVEL ORAL ANTICOAGULANTS
Patterns of tertiary prophylaxis in C anadian adults with severe and moderately severe haemophilia B


Comparisons between novel oral anticoagulants and vitamin K antagonists in patients with CKD
Case report: recurrent disseminated intravascular coagulation caused by intermittent dosing of rifampin

Myelodysplastic syndrome and alloimmunization: The impact of prophylactic Rh and Kell matching for red cell transfusion
The Canadian Massive Transfusion Consensus Conference Proceedings
Thrombopoietin (TPO)-receptor agonists in myelodysplastic syndromes (MDS): a systematic review and meta-analysis
Surgery in FVIII inhibitor patients: single center experience of 13 procedures in 8 patients
Current status and future prospects for the prophylactic management of hemophilia patients with inhibitor antibodies
Pre-Operative Coagulation Test Results Do Not Correlate with Self-Bleeding Assessment Tool (Self-BAT) Scores
Facilitators and Barriers to Accessing Antifibrinolytic and Iron Therapies for Patients Who Menstruate-a Global Healthcare Provider Survey
Initial Report of Part B Phase 1/2 Efficacy and Safety Results for Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed Immune Thrombocytopenia
Evaluating Hemoglobin Thresholds on the Basis of Sex: Preliminary Insights from a Systematic Review
An Approach to Hemequity: Identifying the Barriers and Enablers of Iron Deficiency Reduction Strategies in Low-to-Middle-Income Countries
High Prevalence of Subjective Minimizing Language in Clinical Trials of Hematologic Malignancies: Natural Language Processing (NLP) Validation Study and Systematic Review of Randomized Controlled Trials Presented at ASH 2009-2021
Evaluating Sex-Based Hemoglobin Reference Intervals Using Strict Definitions of Health
Iron Surveillance and Management in Gastro-Intestinal Oncology Patients: A National Physician Survey
Evaluation of the association of factor XIII at hospital arrival and outcomes in a cohort of severely injured patients
Safety Profile of Efgartigimod from Clinical Trials in Participants with Immunoglobulin G-Mediated Autoimmune Diseases
Obstetrical Decision-Making in Moderate or Severe Hemophilia A and B: A Qualitative Study Exploring Parents' Experiences, Preferences and Needs
A Multicentre Cohort Study Evaluating Pregnancy Loss in Patients with Von Willebrand Disease and Unspecified Bleeding Disorders
Evaluation of the Association of Factor XIII at Hospital Arrival and Outcomes in a Cohort of Severely Injured Patients
Delphi Consensus Recommendations for Neuraxial Anesthesia in Adults with Platelet Disorders and Coagulation Defects
Factor XIII 24-Hour Trajectory Analysis in Severely Injured Patients: Post-hoc Analysis of the Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Study
“Reclassifying hemophilia to include the definition of outcomes and phenotype as new targets”: Reply
Gastrointestinal bleeding in von Willebrand patients: special diagnostic and management considerations
Reclassifying hemophilia to include the definition of outcomes and phenotype as new targets
Defining ferritin clinical decision limits to improve diagnosis and treatment of iron deficiency: A modified Delphi study
A pilot feasibility trial of daily versus every other day oral iron supplementation in patients with iron deficiency anaemia.
Prevalence of iron deficiency and iron-deficiency anemia in US females aged 12-21 years, 2003-2020
Antithrombotic treatment in patients with hemophilia: an EHA-ISTH-EAHAD-ESO clinical practice guidance
Association between diabetes and mortality among adult patients hospitalized with COVID-19: A cohort study of hospitalized adults in ontario, canada, and copenhagen, denmark
Vaginal Blood Loss: A patient-and medical trainee-centered mixed-methods research program
PERI-OPERATIVE ORTHOPEDIC MANAGEMENT OF A PATIENT WITH SEVERE HEMOPHILIA A AND A FACTOR VIII INHIBITOR ON EMICIZUMAB
THE ORIGIN OF FERRITIN REFERENCE INTERVALS: A SYSTEMATIC REVIEW
THE FREQUENCY AND SIGNIFICANCE OF CROSSREACTING ANTI-PORCINE FVIII INHIBITORS IN PATIENTS WITH CONGENITAL AND ACQUIRED HEMOPHILIA A
A CASE OF LYMPHOMA-ASSOCIATED ACQUIRED VON WILLEBRAND SYNDROME RESPONSIVE TO SPLENECTOMY
Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management
Perioperative continuous infusions of factor VIII versus factor IX for patients with hemophilia A or B undergoing major surgery